{"id":8859,"date":"2026-03-18T10:00:41","date_gmt":"2026-03-18T01:00:41","guid":{"rendered":"https:\/\/www.kaku-ichi.co.jp\/media\/?p=8859"},"modified":"2026-02-23T09:31:29","modified_gmt":"2026-02-23T00:31:29","slug":"the-process-leading-to-drug-resistance","status":"publish","type":"post","link":"https:\/\/www.kaku-ichi.co.jp\/media\/tips\/column\/the-process-leading-to-drug-resistance","title":{"rendered":"\u85ac\u5264\u62b5\u6297\u6027\u7372\u5f97\u307e\u3067\u306e\u6d41\u308c\u3002\u306a\u305c\u5bb3\u866b\u306f\u85ac\u5264\u62b5\u6297\u6027\u3092\u5f97\u3066\u3057\u307e\u3046\u306e\u304b\u3002"},"content":{"rendered":"<p>\u8fb2\u696d\u751f\u7523\u306b\u304a\u3044\u3066\u3001\u8fb2\u85ac\u306f\u75c5\u5bb3\u866b\u3084\u96d1\u8349\u306e\u88ab\u5bb3\u3092\u9632\u3050\u91cd\u8981\u306a\u624b\u6bb5\u3067\u3059\u3002\u3057\u304b\u3057\u3001\u9577\u5e74\u540c\u3058\u85ac\u5264\u3092\u7e70\u308a\u8fd4\u3057\u4f7f\u3046\u3046\u3061\u306b\u3001\u305d\u306e\u85ac\u5264\u3092\u4f7f\u3063\u3066\u3082\u52b9\u679c\u304c\u51fa\u305a\u3001\u88ab\u5bb3\u304c\u9032\u884c\u3057\u3066\u3057\u307e\u3046\u73fe\u8c61\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u308c\u306f\u300c\u85ac\u5264\u62b5\u6297\u6027\u300d\u3068\u547c\u3070\u308c\u308b\u73fe\u8c61\u3067\u3059\u3002\u85ac\u5264\u62b5\u6297\u6027\u306f\u3001\u5bb3\u866b\u3084\u75c5\u539f\u83cc\u306a\u3069\u304c\u8fb2\u85ac\u306e\u9023\u7d9a\u4f7f\u7528\u306b\u3088\u308a\u3001\u305d\u306e\u85ac\u5264\u306b\u5bfe\u3059\u308b\u89e3\u6bd2\u80fd\u529b\u3084\u9632\u5fa1\u529b\u3092\u7372\u5f97\u3057\u3001\u52b9\u679c\u304c\u4f4e\u4e0b\u3059\u308b\u73fe\u8c61\u3092\u6307\u3057\u3001\u5404\u5730\u3067\u898b\u3089\u308c\u308b\u3088\u3046\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u3053\u3046\u3057\u305f\u62b5\u6297\u6027\u306e\u767a\u9054\u306f\u8fb2\u85ac\u306e\u52b9\u679c\u4f4e\u4e0b\u3092\u62db\u304d\u3001\u8fb2\u696d\u306e\u6301\u7d9a\u53ef\u80fd\u6027\u306b\u3082\u5927\u304d\u306a\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u80cc\u666f\u3084\u4ed5\u7d44\u307f\u3092\u7406\u89e3\u3059\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/p>\n<p>\u203b\u306a\u304a\u3001\u672c\u8a18\u4e8b\u3067\u306f\u300c\u62b5\u6297\u6027\u300d\u3068\u300c\u8010\u6027\u300d\u3092\u540c\u7fa9\u306e\u8868\u73fe\u3068\u3057\u3066\u7528\u3044\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<h2 id=\"outline__1\">\u3042\u3089\u305f\u3081\u3066\u85ac\u5264\u62b5\u6297\u6027\u3068\u306f<\/h2>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-8883\" src=\"https:\/\/www.kaku-ichi.co.jp\/media\/wp-content\/uploads\/2026\/03\/20260318001.jpg\" alt=\"\u85ac\u5264\u62b5\u6297\u6027\u7372\u5f97\u307e\u3067\u306e\u6d41\u308c\u3002\u306a\u305c\u5bb3\u866b\u306f\u85ac\u5264\u62b5\u6297\u6027\u3092\u5f97\u3066\u3057\u307e\u3046\u306e\u304b\u3002\uff5c\u753b\u50cf\uff11\" width=\"640\" height=\"480\" \/><\/p>\n<p>&nbsp;<\/p>\n<p>\u524d\u8ff0\u3057\u305f\u901a\u308a\u3001\u85ac\u5264\u62b5\u6297\u6027\u306f\u3001\u3042\u308b\u85ac\u5264\u304c\u4ee5\u524d\u306f\u52b9\u679c\u7684\u3060\u3063\u305f\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u3001\u540c\u3058\u85ac\u5264\u3092\u4f7f\u7528\u3057\u3066\u3082\u671f\u5f85\u3057\u305f\u52b9\u679c\u304c\u5f97\u3089\u308c\u306a\u304f\u306a\u308b\u73fe\u8c61\u3092\u6307\u3057\u307e\u3059\u3002<\/p>\n<p>\u4ee5\u4e0b\u306e\u8aac\u660e\u306f\u3001\u7814\u7a76\u7528\u8a9e\u8f9e\u5178\u300c\u85ac\u5264\u8010\u6027\u300d\u306e1\u6587\u3067\u3059\u3002<\/p>\n<blockquote><p>\u85ac\u5264\u8010\u6027\u3068\u306f\u3001\u751f\u7269\u304c\u81ea\u5206\u306b\u5bfe\u3057\u3066\u306a\u3093\u3089\u304b\u306e\u4f5c\u7528\u3092\u3082\u3063\u305f\u85ac\u5264\u306b\u5bfe\u3057\u3066\u62b5\u6297\u6027\u3092\u6301\u3061\u3001\u3053\u308c\u3089\u306e\u85ac\u5264\u304c\u52b9\u304b\u306a\u3044\u3001\u3082\u3057\u304f\u306f\u52b9\u304d\u306b\u304f\u304f\u306a\u308b\u73fe\u8c61\u306e\u3053\u3068\u3067\u3059\u3002\u591a\u304f\u306e\u5834\u5408\u3001\u533b\u5b66\u30fb\u75c5\u7406\u5b66\u3001\u751f\u7269\u5b66\u306e\u5206\u91ce\u3067\u306f\u3001\u7d30\u83cc\u3084\u30a6\u30a4\u30eb\u30b9\u306b\u5bfe\u3057\u3066\u85ac\u5264\u304c\u52b9\u304b\u306a\u3044\u3001\u307e\u305f\u306f\u52b9\u304d\u306b\u304f\u304f\u306a\u308b\u3053\u3068\u3092\u6307\u3057\u3001\u8fb2\u5b66\u306e\u5206\u91ce\u3067\u306f\u6bba\u866b\u5264\u306b\u5bfe\u3059\u308b\u75c5\u5bb3\u866b\u306e\u8010\u6027\u3084\u3001\u9664\u8349\u5264\u306b\u5bfe\u3059\u308b\u690d\u7269\u306e\u8010\u6027\u3092\u6307\u3057\u307e\u3059\u3002<\/p>\n<p>\u5f15\u7528\u5143\uff1a<a href=\"https:\/\/www.wdb.com\/kenq\/dictionary\/drug-resistance\" target=\"_blank\" rel=\"nofollow noopener\">\u85ac\u5264\u8010\u6027\u3068\u306f\uff5c\u7814\u7a76\u7528\u8a9e\u8f9e\u5178<\/a><\/p><\/blockquote>\n<p>\u3053\u308c\u306f\u5bb3\u866b\u3084\u75c5\u539f\u4f53\u306e\u96c6\u56e3\u304c\u305d\u306e\u85ac\u5264\u306b\u8010\u6027\u3092\u6301\u3064\u3088\u3046\u306b\u306a\u3063\u305f\u7d50\u679c\u3068\u3057\u3066\u8d77\u3053\u308a\u307e\u3059\u3002\u3053\u306e\u300c\u62b5\u6297\u6027\u300d\u306e\u6a19\u6e96\u7684\u306a\u5b9a\u7fa9\u3068\u3057\u3066\u3001\u5bfe\u8c61\u96c6\u56e3\u304c\u85ac\u5264\u306b\u5bfe\u3057\u3066\u907a\u4f1d\u7684\u306b\u5909\u5316\u3057\u3001\u305d\u306e\u7d50\u679c\u85ac\u5264\u306e\u52b9\u679c\u304c\u3001\u85ac\u5264\u30e9\u30d9\u30eb\u306b\u8a18\u8f09\u3055\u308c\u305f\u901a\u308a\u306b\u4f7f\u3063\u3066\u3082\u3001\u7e70\u308a\u8fd4\u3057\u671f\u5f85\u3057\u305f\u9632\u9664\u52b9\u679c\u304c\u5f97\u3089\u308c\u306a\u3044\u72b6\u614b\u3001\u3068\u3055\u308c\u3066\u3044\u307e\u3059\u3002\uff08\u53c2\u7167\u5143\uff1a<a href=\"https:\/\/irac-online.org\/training-centre\/resistance\/\" target=\"_blank\" rel=\"nofollow noopener\">Introduction to Resistance | Insecticide Resistance Action Commiee (Insecticide Resistance Action Committee<\/a> \uff09<\/p>\n<p>\u3053\u306e\u62b5\u6297\u6027\u306f\u300c\u96c6\u56e3\u30ec\u30d9\u30eb\u306e\u5909\u5316\u300d\u3067\u3042\u308a\u3001\u5168\u3066\u306e\u500b\u4f53\u304c\u5909\u5316\u3059\u308b\u308f\u3051\u3067\u306f\u306a\u3044\u3068\u3053\u308d\u304c\u91cd\u8981\u306a\u70b9\u3067\u3059\u3002\u521d\u3081\u306f\u3054\u304f\u308f\u305a\u304b\u306a\u500b\u4f53\u304c\u62b5\u6297\u6027\u306e\u907a\u4f1d\u5b50\u3092\u6301\u3061\u307e\u3059\u3002\u3057\u304b\u3057\u5f8c\u8ff0\u3059\u308b\u3088\u3046\u306b\u3001\u300c\u9078\u629e\u5727\u300d\u304c\u304b\u304b\u308b\u3053\u3068\u3067\u62b5\u6297\u6027\u306e\u907a\u4f1d\u5b50\u3092\u6301\u3063\u305f\u500b\u4f53\u306e\u5272\u5408\u304c\u5897\u3048\u3066\u3044\u304d\u307e\u3059\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<h2 id=\"outline__2\">\u85ac\u5264\u62b5\u6297\u6027\u7372\u5f97\u306e\u4e00\u822c\u7684\u306a\u6d41\u308c<\/h2>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-8884\" src=\"https:\/\/www.kaku-ichi.co.jp\/media\/wp-content\/uploads\/2026\/03\/20260318002.jpg\" alt=\"\u85ac\u5264\u62b5\u6297\u6027\u7372\u5f97\u307e\u3067\u306e\u6d41\u308c\u3002\u306a\u305c\u5bb3\u866b\u306f\u85ac\u5264\u62b5\u6297\u6027\u3092\u5f97\u3066\u3057\u307e\u3046\u306e\u304b\u3002\uff5c\u753b\u50cf\uff12\" width=\"640\" height=\"466\" \/><\/p>\n<p>&nbsp;<\/p>\n<p>\u85ac\u5264\u62b5\u6297\u6027\u306f\u6b21\u306e\u3088\u3046\u306a\u6d41\u308c\u3067\u9032\u307f\u307e\u3059\u3002<\/p>\n<h3 id=\"outline__2_1\">1.\u62b5\u6297\u6027\u3092\u3082\u3064\u500b\u4f53\u306e\u5b58\u5728<\/h3>\n<p>\u81ea\u7136\u754c\u306e\u5bb3\u866b\u96c6\u56e3\u306b\u306f\u3001\u75c5\u539f\u83cc\u3084\u6606\u866b\u3092\u554f\u308f\u305a\u3001\u308f\u305a\u304b\u306b\u85ac\u5264\u306b\u5bfe\u3057\u3066\u8010\u6027\u3092\u3082\u3064\u907a\u4f1d\u7684\u5909\u7570\u3092\u6301\u3064\u500b\u4f53\u304c\u5b58\u5728\u3057\u307e\u3059\u3002\u3053\u306e\u5909\u7570\u306f\u5b8c\u5168\u306b\u65b0\u3057\u304f\u751f\u307e\u308c\u308b\u3082\u306e\u3060\u3051\u3067\u306a\u304f\u3001\u85ac\u5264\u4ee5\u5916\u306e\u74b0\u5883\u8981\u56e0\u3067\u9032\u5316\u3057\u3066\u304d\u305f\u5909\u7570\u304c\u85ac\u5264\u306b\u5bfe\u3059\u308b\u8010\u6027\u3092\u3082\u305f\u3089\u3059\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n<h3 id=\"outline__2_2\">2.\u85ac\u5264\u4f7f\u7528\u306b\u3088\u308b\u5f37\u3044\u9078\u629e\u5727<\/h3>\n<p>\u300c\u9078\u629e\u5727\u300d\u3068\u306f<\/p>\n<blockquote><p>\u751f\u7269\u306e\u9032\u5316\u306b\u304a\u3044\u3066\u3001\u3042\u308b\u5f62\u8cea\u3092\u3082\u3064\u751f\u7269\u500b\u4f53\u306b\u306f\u305f\u3089\u304f\u81ea\u7136\u9078\u629e\u306e\u4f5c\u7528\u3002\u74b0\u5883\u6761\u4ef6\u3084\u4ed6\u7a2e\u3068\u306e\u7af6\u5408\u3001\u5929\u6575\u306b\u3088\u308b\u6355\u98df\u306a\u3069\u306b\u3088\u3063\u3066\u751f\u3058\u308b\u3002\u6dd8\u6c70\u5727\u3002<\/p>\n<p>\u51fa\u5178\uff1a\u30c7\u30b8\u30bf\u30eb\u5927\u8f9e\u6cc9\uff08\u5c0f\u5b66\u9928\uff09<\/p><\/blockquote>\n<p>\u3068\u3044\u3046\u610f\u5473\u3067\u3059\u3002<\/p>\n<p>\u75c5\u5bb3\u866b\u304b\u3089\u4f5c\u7269\u3092\u5b88\u308b\u305f\u3081\u306b\u8fb2\u85ac\u3092\u6563\u5e03\u3059\u308b\u3068\u3001\u591a\u304f\u306e\u500b\u4f53\u306f\u85ac\u5264\u306b\u3088\u308a\u6b7b\u6ec5\u3057\u307e\u3059\u3002\u3057\u304b\u3057\u30011.\u3067\u8aac\u660e\u3057\u305f\u3088\u3046\u306b\u3001\u308f\u305a\u304b\u306b\u5b58\u5728\u3059\u308b\u300c\u8010\u6027\u3092\u6301\u3064\u500b\u4f53\u300d\u306f\u751f\u304d\u6b8b\u308a\u307e\u3059\u3002\u3053\u306e\u6642\u3001\u85ac\u5264\u304c\u52a0\u3048\u308b\u5f37\u3044\u9078\u629e\u5727\u306b\u3088\u3063\u3066\u8010\u6027\u3092\u3082\u3064\u500b\u4f53\u306e\u751f\u5b58\u7387\u304c\u9ad8\u307e\u308a\u3001\u305d\u306e\u5b50\u5b6b\u304c\u5897\u3048\u3066\u3044\u304d\u307e\u3059\u3002\u751f\u5b58\u3057\u305f\u500b\u4f53\u306e\u5b50\u5b6b\u304c\u5897\u3048\u308b\u306b\u3064\u308c\u3001\u8010\u6027\u907a\u4f1d\u5b50\u306e\u5272\u5408\u306f\u6025\u901f\u306b\u9ad8\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n<h3 id=\"outline__2_3\">3.\u4e16\u4ee3\u4ea4\u4ee3\u306b\u3088\u308b\u907a\u4f1d\u7684\u5909\u5316\u306e\u5897\u52a0<\/h3>\n<p>\u591a\u304f\u306e\u8fb2\u696d\u5bb3\u866b\u3084\u75c5\u539f\u83cc\u306f\u4e16\u4ee3\u4ea4\u4ee3\u304c\u65e9\u304f\u30011\u5e74\u306b\u4f55\u5ea6\u3082\u7e41\u6b96\u3092\u7e70\u308a\u8fd4\u3057\u307e\u3059\u3002\u307e\u305f\u4e00\u5ea6\u306e\u7e41\u6b96\u3067\u591a\u6570\u306e\u5b50\u5b6b\u3092\u6b8b\u3059\u7a2e\u3082\u5c11\u306a\u304f\u3042\u308a\u307e\u305b\u3093\u3002\u3053\u308c\u306f\u8010\u6027\u907a\u4f1d\u5b50\u304c\u96c6\u56e3\u5185\u306b\u5e83\u304c\u308b\u901f\u5ea6\u3092\u52a0\u901f\u3059\u308b\u3082\u306e\u3067\u3059\u3002\u305f\u3068\u3048\u3070\u3001\u6570\u4e16\u4ee3\u306e\u3046\u3061\u306b\u62b5\u6297\u6027\u907a\u4f1d\u5b50\u304c\u96c6\u56e3\u5185\u3067\u4e3b\u6d41\u306b\u306a\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n<h3 id=\"outline__2_4\">4.\u62b5\u6297\u6027\u96c6\u56e3\u306e\u56fa\u5b9a\u5316<\/h3>\n<p>\u6700\u7d42\u7684\u306b\u3001\u96c6\u56e3\u5168\u4f53\u306e\u5927\u591a\u6570\u304c\u8010\u6027\u907a\u4f1d\u5b50\u3092\u6301\u3064\u3088\u3046\u306b\u306a\u308b\u3068\u3001\u85ac\u5264\u306e\u52b9\u679c\u304c\u8457\u3057\u304f\u4f4e\u4e0b\u3057\u307e\u3059\u3002\u3053\u306e\u72b6\u614b\u306b\u306a\u308b\u3068\u3001\u540c\u3058\u85ac\u5264\u3092\u4f7f\u7528\u3057\u3066\u3082\u671f\u5f85\u3057\u305f\u9632\u9664\u52b9\u679c\u306f\u307b\u307c\u5f97\u3089\u308c\u306a\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<h2 id=\"outline__3\">\u751f\u7269\u5074\u306e\u5909\u7570\u306e\u30e1\u30ab\u30cb\u30ba\u30e0<\/h2>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-8885\" src=\"https:\/\/www.kaku-ichi.co.jp\/media\/wp-content\/uploads\/2026\/03\/20260318003.jpg\" alt=\"\u85ac\u5264\u62b5\u6297\u6027\u7372\u5f97\u307e\u3067\u306e\u6d41\u308c\u3002\u306a\u305c\u5bb3\u866b\u306f\u85ac\u5264\u62b5\u6297\u6027\u3092\u5f97\u3066\u3057\u307e\u3046\u306e\u304b\u3002\uff5c\u753b\u50cf\uff13\" width=\"640\" height=\"427\" \/><\/p>\n<p>&nbsp;<\/p>\n<p>\u62b5\u6297\u6027\u7372\u5f97\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u306f\u8907\u6570\u3042\u308a\u307e\u3059\u304c\u3001\u4ee3\u8868\u7684\u306a\u3082\u306e\u3092\u7d39\u4ecb\u3057\u307e\u3059\u3002<\/p>\n<h3 id=\"outline__3_1\">\u4ee3\u8b1d\u578b\u62b5\u6297\u6027\uff08Metabolic Resistance\uff09<\/h3>\n<p>\u4ee3\u8b1d\u578b\u62b5\u6297\u6027\u306f\u6700\u3082\u4e00\u822c\u7684\u306a\u62b5\u6297\u6027\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u4e00\u3064\u3067\u3059\u3002\u5bb3\u866b\u306f\u4f53\u5185\u9175\u7d20\u3092\u4f7f\u3044\u3001\u85ac\u5264\u3092\u5206\u89e3\u307e\u305f\u306f\u7121\u5bb3\u5316\u3059\u308b\u3053\u3068\u3067\u6bd2\u6027\u3092\u907f\u3051\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u5177\u4f53\u7684\u306b\u306f\u3001\u30b7\u30c8\u30af\u30ed\u30e0P450\u3084\u30a8\u30b9\u30c6\u30e9\u30fc\u30bc\u3001\u30b0\u30eb\u30bf\u30c1\u30aa\u30f3-S-\u30c8\u30e9\u30f3\u30b9\u30d5\u30a7\u30e9\u30fc\u30bc\u3068\u3044\u3063\u305f\u9175\u7d20\u304c\u8fb2\u85ac\u3092\u5206\u89e3\u3057\u3001\u4f5c\u7528\u3092\u5f31\u3081\u308b\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u3059\u3002<\/p>\n<h3 id=\"outline__3_2\">\u4f5c\u7528\u90e8\u4f4d\u5909\u7570\uff08Target-site Resistance\uff09<\/h3>\n<p>\u85ac\u5264\u304c\u672c\u6765\u7d50\u5408\u3057\u3066\u5bb3\u866b\u3092\u6bba\u3059\u6a19\u7684\u3068\u306a\u308b\u5206\u5b50\uff08\u305f\u3068\u3048\u3070\u795e\u7d4c\u7cfb\u306e\u53d7\u5bb9\u4f53\uff09\u306b\u5909\u7570\u304c\u751f\u3058\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u305d\u306e\u7d50\u679c\u3001\u85ac\u5264\u304c\u3046\u307e\u304f\u7d50\u5408\u3067\u304d\u305a\u3001\u6bba\u866b\u52b9\u679c\u304c\u767a\u63ee\u3055\u308c\u306b\u304f\u304f\u306a\u308a\u307e\u3059\u3002\u3053\u3046\u3057\u305f\u6a19\u7684\u90e8\u4f4d\u306e\u5909\u7570\u306f\u9ad8\u3044\u62b5\u6297\u6027\u3092\u793a\u3057\u307e\u3059\u3002<\/p>\n<h3 id=\"outline__3_3\">\u884c\u52d5\u62b5\u6297\u6027\uff08Behavioral Resistance\uff09<\/h3>\n<p>\u5bb3\u866b\u304c\u85ac\u5264\u306e\u5b58\u5728\u3092\u5bdf\u77e5\u3057\u3001\u85ac\u5264\u304c\u6563\u5e03\u3055\u308c\u305f\u5834\u6240\u3092\u907f\u3051\u308b\u3088\u3046\u306a\u884c\u52d5\u5909\u5316\u3092\u3059\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002\u305f\u3068\u3048\u3070\u6563\u5e03\u76f4\u5f8c\u306b\u8449\u306e\u88cf\u5074\u306b\u79fb\u52d5\u3057\u305f\u308a\u3001\u85ac\u5264\u3092\u907f\u3051\u3066\u98db\u3073\u7acb\u3064\u3068\u3044\u3063\u305f\u884c\u52d5\u30d1\u30bf\u30fc\u30f3\u306e\u5909\u5316\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<h3 id=\"outline__3_4\">\u4fb5\u5165\u30fb\u5438\u53ce\u62b5\u6297\u6027\uff08Penetration Resistance\uff09<\/h3>\n<p>\u5bb3\u866b\u306e\u5916\u76ae\u306b\u5909\u5316\u304c\u751f\u3058\u3001\u85ac\u5264\u304c\u4f53\u5185\u306b\u6d78\u900f\u3057\u306b\u304f\u304f\u306a\u308b\u3053\u3068\u3067\u62b5\u6297\u6027\u3092\u793a\u3059\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u306e\u5f62\u5f0f\u306e\u62b5\u6297\u6027\u306f\u4ed6\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u3068\u7d44\u307f\u5408\u308f\u3055\u308b\u3053\u3068\u304c\u591a\u3044\u3067\u3059\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<h2 id=\"outline__4\">\u85ac\u5264\u62b5\u6297\u6027\u3092\u9632\u3050\u305f\u3081\u306e\u5bfe\u7b56<\/h2>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-8886\" src=\"https:\/\/www.kaku-ichi.co.jp\/media\/wp-content\/uploads\/2026\/03\/20260318004.jpg\" alt=\"\u85ac\u5264\u62b5\u6297\u6027\u7372\u5f97\u307e\u3067\u306e\u6d41\u308c\u3002\u306a\u305c\u5bb3\u866b\u306f\u85ac\u5264\u62b5\u6297\u6027\u3092\u5f97\u3066\u3057\u307e\u3046\u306e\u304b\u3002\uff5c\u753b\u50cf\uff14\" width=\"640\" height=\"480\" \/><\/p>\n<p>&nbsp;<\/p>\n<p>\u85ac\u5264\u62b5\u6297\u6027\u3092\u5b8c\u5168\u306b\u9632\u3050\u3053\u3068\u306f\u96e3\u3057\u3044\u3067\u3059\u304c\u3001\u767a\u9054\u3092\u9045\u3089\u305b\u305f\u308a\u5f71\u97ff\u3092\u7de9\u548c\u3059\u308b\u5b9f\u8df5\u7684\u306a\u5bfe\u7b56\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n<p>\u4ee3\u8868\u7684\u306a\u3082\u306e\u306b\u306f\u3001\u4f5c\u7528\u6a5f\u69cb\u306e\u7570\u306a\u308b\u85ac\u5264\u3092\u4ea4\u4e92\u306b\u4f7f\u7528\u3059\u308b\u3053\u3068\u304c\u3042\u3052\u3089\u308c\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u4e00\u7a2e\u985e\u306e\u62b5\u6297\u6027\u304c\u96c6\u56e3\u5185\u3067\u56fa\u5b9a\u3059\u308b\u30ea\u30b9\u30af\u3092\u4e0b\u3052\u307e\u3059\u3002\u307e\u305f\u3001IPM(\u7dcf\u5408\u7684\u75c5\u5bb3\u866b\u30fb\u96d1\u8349\u7ba1\u7406\uff09\u306e\u5c0e\u5165\u3082\u6709\u52b9\u3067\u3059\u3002\u3053\u308c\u306f\u75c5\u5bb3\u866b\u9632\u9664\u3092\u85ac\u5264\u3060\u3051\u306b\u983c\u3089\u305a\u3001\u8015\u7a2e\u7684\u9632\u9664\uff08\u54c1\u7a2e\u9078\u629e\u3001\u4f5c\u7269\u8f2a\u4f5c\u306a\u3069\uff09\u3001\u7269\u7406\u7684\u9632\u9664\uff08\u30cd\u30c3\u30c8\u3001\u9632\u866b\u30b7\u30fc\u30c8\uff09\u3001\u751f\u7269\u7684\u9632\u9664\uff08\u5929\u6575\u5229\u7528\uff09\u3092\u7d44\u307f\u5408\u308f\u305b\u308b\u3053\u3068\u3067\u3001\u85ac\u5264\u3078\u306e\u4f9d\u5b58\u5ea6\u3092\u4e0b\u3052\u308b\u65b9\u6cd5\u3067\u3059\u3002<\/p>\n<p>\u307e\u305f\u3001\u62b5\u6297\u6027\u767a\u751f\u306e\u5146\u5019\u3092\u65e9\u671f\u306b\u628a\u63e1\u3059\u308b\u305f\u3081\u3001\u30d5\u30a3\u30fc\u30eb\u30c9\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u3084\u85ac\u5264\u611f\u53d7\u6027\u8a66\u9a13\u3092\u5b9f\u65bd\u3057\u3001\u62b5\u6297\u6027\u306e\u767a\u9054\u3092\u898b\u6975\u3081\u308b\u3053\u3068\u3082\u91cd\u8981\u3067\u3059\u3002\u305d\u306e\u307b\u304b\u3001\u85ac\u5264\u3092\u6563\u5e03\u3057\u306a\u3044\u533a\u57df\u3092\u8a2d\u3051\u3001\u611f\u53d7\u6027\u500b\u4f53\u306e\u907a\u4f1d\u5b50\u3092\u96c6\u56e3\u306b\u7dad\u6301\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u62b5\u6297\u6027\u907a\u4f1d\u5b50\u306e\u5272\u5408\u306e\u6025\u5897\u3092\u6291\u3048\u308b\u3068\u3044\u3063\u305f\u6226\u7565\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<h2 id=\"outline__5\">\u307e\u3068\u3081<\/h2>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-8887\" src=\"https:\/\/www.kaku-ichi.co.jp\/media\/wp-content\/uploads\/2026\/03\/20260318005.jpg\" alt=\"\u85ac\u5264\u62b5\u6297\u6027\u7372\u5f97\u307e\u3067\u306e\u6d41\u308c\u3002\u306a\u305c\u5bb3\u866b\u306f\u85ac\u5264\u62b5\u6297\u6027\u3092\u5f97\u3066\u3057\u307e\u3046\u306e\u304b\u3002\uff5c\u753b\u50cf\uff15\" width=\"640\" height=\"427\" \/><\/p>\n<p>&nbsp;<\/p>\n<p>\u85ac\u5264\u62b5\u6297\u6027\u306f\u3001\u8fb2\u85ac\u304c\u52b9\u679c\u3092\u6301\u3064\u74b0\u5883\u4e0b\u3067\u5bb3\u866b\u96c6\u56e3\u306b\u5f37\u3044\u9078\u629e\u5727\u304c\u52a0\u308f\u308b\u3068\u3001\u62b5\u6297\u6027\u907a\u4f1d\u5b50\u3092\u6301\u3064\u500b\u4f53\u304c\u751f\u304d\u6b8b\u308a\u3001\u4e16\u4ee3\u4ea4\u4ee3\u3092\u7d4c\u3066\u62b5\u6297\u6027\u304c\u96c6\u56e3\u5185\u3067\u5897\u3048\u308b\u3053\u3068\u3067\u8d77\u3053\u308a\u307e\u3059\u3002\u3053\u306e\u30d7\u30ed\u30bb\u30b9\u306f\u77ed\u671f\u9593\u3067\u3082\u9032\u884c\u3057\u3084\u3059\u304f\u3001\u500b\u4f53\u306e\u4ee3\u8b1d\u80fd\u529b\u3084\u4f5c\u7528\u90e8\u4f4d\u306e\u5909\u7570\u3001\u884c\u52d5\u5909\u5316\u3068\u3044\u3063\u305f\u591a\u69d8\u306a\u30e1\u30ab\u30cb\u30ba\u30e0\u304c\u95a2\u4e0e\u3057\u307e\u3059\u3002<\/p>\n<p>\u62b5\u6297\u6027\u306e\u767a\u9054\u3092\u6291\u3048\u308b\u305f\u3081\u306b\u306f\u3001\u85ac\u5264\u306e\u4f5c\u7528\u6a5f\u69cb\u306e\u30ed\u30fc\u30c6\u30fc\u30b7\u30e7\u30f3\u3084\u85ac\u5264\u4ee5\u5916\u306e\u9632\u9664\u624b\u6bb5\u3092\u53d6\u308a\u5165\u308c\u305f\u7dcf\u5408\u7684\u306a\u5bb3\u866b\u7ba1\u7406\u304c\u4e0d\u53ef\u6b20\u3067\u3059\u3002\u307e\u305f\u3001\u62b5\u6297\u6027\u306e\u65e9\u671f\u767a\u898b\u3068\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u304c\u52b9\u679c\u7684\u306a\u5bfe\u7b56\u8a08\u753b\u306e\u57fa\u76e4\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n<p><a href=\"https:\/\/www.maff.go.jp\/j\/syouan\/syokubo\/gaicyu\/yakuzai.html\" target=\"_blank\" rel=\"nofollow noopener\">\u85ac\u5264\u62b5\u6297\u6027\u5bfe\u7b56\u306b\u95a2\u3059\u308b\u60c5\u5831<\/a><\/p>\n<p>&nbsp;<\/p>\n<p>\u53c2\u7167\u30b5\u30a4\u30c8<\/p>\n<ul>\n<li><a href=\"https:\/\/irac-online.org\/training-centre\/resistance\/\" target=\"_blank\" rel=\"nofollow noopener\">Introduction to Resistance | Insecticide Resistance Action Commiee (Insecticide Resistance Action Committee)<\/a><\/li>\n<li><a href=\"https:\/\/www.naro.go.jp\/laboratory\/nias\/contents\/files\/C1_2.pdf\" target=\"_blank\" rel=\"nofollow noopener\">1-2 \u85ac\u5264\u62b5\u6297\u6027\u7ba1\u7406\u306e\u8003\u3048\u65b9<\/a><\/li>\n<li><a href=\"https:\/\/www.fmc-japan.com\/trendinfo\/irac\/04\" target=\"_blank\" rel=\"nofollow noopener\">IRM\uff08\u6bba\u866b\u5264\u62b5\u6297\u6027\u7ba1\u7406\uff09<\/a><\/li>\n<li><a href=\"https:\/\/www.toho-u.ac.jp\/sci\/bio\/column\/0831.html\" target=\"_blank\" rel=\"nofollow noopener\">\u9664\u8349\u5264\u62b5\u6297\u6027\u96d1\u8349\u306e\u51fa\u73fe\u3068\u79fb\u5165 | \u7406\u5b66\u90e8 | \u6771\u90a6\u5927\u5b66<\/a><\/li>\n<li><a href=\"https:\/\/www.maff.go.jp\/j\/syouan\/syokubo\/gaicyu\/attach\/pdf\/yakuzai-2.pdf\" target=\"_blank\" rel=\"nofollow noopener\">\u85ac\u5264\u62b5\u6297\u6027\u5bfe\u7b56\u306e\u73fe\u72b6\u3068\u4eca\u5f8c\u306e\u5bfe\u7b56<\/a><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>\u8fb2\u696d\u751f\u7523\u306b\u304a\u3044\u3066\u3001\u8fb2\u85ac\u306f\u75c5\u5bb3\u866b\u3084\u96d1\u8349\u306e\u88ab\u5bb3\u3092\u9632\u3050\u91cd\u8981\u306a\u624b\u6bb5\u3067\u3059\u3002\u3057\u304b\u3057\u3001\u9577\u5e74\u540c\u3058\u85ac\u5264\u3092\u7e70\u308a\u8fd4\u3057\u4f7f\u3046\u3046\u3061\u306b\u3001\u305d\u306e\u85ac\u5264\u3092\u4f7f\u3063\u3066\u3082\u52b9\u679c\u304c\u51fa\u305a\u3001\u88ab\u5bb3&#8230; <a href=\"https:\/\/www.kaku-ichi.co.jp\/media\/tips\/column\/the-process-leading-to-drug-resistance\"><font color=\"6bb643\">\u3010\u7d9a\u304d\u3092\u8aad\u3080\u3011<\/font><\/a><\/p>\n","protected":false},"author":2,"featured_media":8883,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[28],"tags":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.kaku-ichi.co.jp\/media\/wp-json\/wp\/v2\/posts\/8859"}],"collection":[{"href":"https:\/\/www.kaku-ichi.co.jp\/media\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.kaku-ichi.co.jp\/media\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.kaku-ichi.co.jp\/media\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.kaku-ichi.co.jp\/media\/wp-json\/wp\/v2\/comments?post=8859"}],"version-history":[{"count":2,"href":"https:\/\/www.kaku-ichi.co.jp\/media\/wp-json\/wp\/v2\/posts\/8859\/revisions"}],"predecessor-version":[{"id":8888,"href":"https:\/\/www.kaku-ichi.co.jp\/media\/wp-json\/wp\/v2\/posts\/8859\/revisions\/8888"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.kaku-ichi.co.jp\/media\/wp-json\/wp\/v2\/media\/8883"}],"wp:attachment":[{"href":"https:\/\/www.kaku-ichi.co.jp\/media\/wp-json\/wp\/v2\/media?parent=8859"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.kaku-ichi.co.jp\/media\/wp-json\/wp\/v2\/categories?post=8859"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.kaku-ichi.co.jp\/media\/wp-json\/wp\/v2\/tags?post=8859"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}